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Year : 2010  |  Volume : 1  |  Issue : 2  |  Page : 112-121

Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) - validation of the Ayurvedic pharmacology through experimental and clinical studies

1 Department of Ayurved Research and Development, Patanjali Yogpeeth, Haridwar, India
2 Patanjali Herbal Garden and Agrotech Department, DYMT (SIROs), Patanjali Yogpeeth, Haridwar, India
3 Patanjali Biotech, Patanjali Ayurved Limited, Haridwar, India
4 Department of Dravya Guna, Govt. Ayurvedic College, Gurukul Kangri, Haridwar, India

Correspondence Address:
Avnish K Upadhyay
Department of Ayurved Research & Development, DYMT (SIROs), Patanjali Yogpeeth, Haridwar, Uttarakhand
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DOI: 10.4103/0974-7788.64405

PMID: 20814526

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T. cordifolia (Guduchi) is a large, glabrous, perennial, deciduous, climbing shrub of weak and fleshy stem found throughout India. It is a widely used plant in folk and Ayurvedic systems of medicine. The chemical constituents reported from this shrub belong to different classes, such as alkaloids, diterpenoid lactones, glycosides, steroids, sesquiterpenoid, phenolics, aliphatic compounds and polysaccharides. Various properties of T. cordifolia, described in ancient texts of Ayurveda, like Rasayana, Sangrahi, Balya, Agnideepana, Tridoshshamaka, Dahnashaka, Mehnashaka, Kasa-swasahara, Pandunashaka, Kamla-Kushta-Vataraktanashaka, Jwarhara, Krimihara, Prameha, Arshnashaka, Kricch-Hridroganashak, etc., are acquiring scientific validity through modern research adopting "reverse pharmacological" approach. Potential medicinal properties reported by scientific research include anti-diabetic, antipyretic, antispasmodic, anti-inflammatory, anti-arthritic, antioxidant, anti-allergic, anti-stress, anti-leprotic, antimalarial, hepato-protective, immuno-modulatory and anti-neoplastic activities. This review brings together various properties and medicinal uses of T. cordifolia described in Ayurveda, along with phytochemical and pharmacological reports.

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