| ORIGINAL ARTICLE |
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Year : 2010 | Volume : 1 | Issue : 3 | Page : 163-166 |
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Antihyperglycemic activity of Tectona grandis Linn. bark extract on alloxan induced diabetes in rats
SB Varma1, DL Jaybhaye2
1 Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha - 402 102, India
2 Department of Pharmacology, Mahatma Gandhi Mission Hospital, Aurangabad - 431 001, Maharashtra, India
Correspondence Address:
D L Jaybhaye
c/o Ramesh Shripatrao Patil, Plot no. 17 Flat No. 5, Vidyanagar Near 7 Hill, Aurangabad - 431 001, Maharashtra
India
DOI: 10.4103/0974-7788.72488
PMID: 21170208
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Tectona Grandis Linn.(saag - tick wood), an indigenous medicinal plant, has a folk reputation among the Indian herbs as a hypoglycemic agent. The present study was carried out to evaluate the anti-hyperglycemic effect of T. grandis Linn. bark extract in control and alloxan-diabetic rats. Oral administration of the bark suspension of T. grandis (2.5 and 5 g/kg body wt.) for 30 days resulted in a significant reduction in blood glucose (from 250 ± 6.5 to 50 ± 2.5 mg/dL). Thus, the present study clearly shows that the T. Grandis Linn. bark extract exerts anti-hyperglycemic activity. |
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